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Table 3 Sensitivity (Sen), specificity (Spec), positive predictive value (PPV) and negative predictive value (NPV) for a range of probability cut-offs for classifying those at high risk of non-response (main model)

From: Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS)

Cut-off Predicted non-responders Sen Spec PPV NPV
0.5 303 (36%) 59% 80% 68% 72%
0.6 210 (25%) 45% 89% 75% 69%
0.7 123 (15%) 30% 96% 86% 65%
0.8 49 (6%) 14% 100% 98% 61%
0.9 13 (2%) 4% 100% 100% 59%