Skip to main content

Table 3 Sensitivity (Sen), specificity (Spec), positive predictive value (PPV) and negative predictive value (NPV) for a range of probability cut-offs for classifying those at high risk of non-response (main model)

From: Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS)

Cut-off

Predicted non-responders

Sen

Spec

PPV

NPV

0.5

303 (36%)

59%

80%

68%

72%

0.6

210 (25%)

45%

89%

75%

69%

0.7

123 (15%)

30%

96%

86%

65%

0.8

49 (6%)

14%

100%

98%

61%

0.9

13 (2%)

4%

100%

100%

59%