Fig. 1From: A randomized controlled trial comparing PF-06438179/GP1111 (an infliximab biosimilar) and infliximab reference product for treatment of moderate to severe active rheumatoid arthritis despite methotrexate therapyStudy design. aA sample size of approximately 614 patients was planned for enrollment; the actual number of patients randomized was 650. bIntravenous PF-06438179/GP1111 or infliximab-EU 3Â mg/kg was given as an induction regimen at weeks 0, 2, and 6, followed by maintenance treatment with a 3Â mg/kg dose starting at week 14 and continuing every 8Â weeks thereafter. Dose escalation to 5Â mg/kg PF-06438179/GP1111 or infliximab-EU was permitted at or after week 14 for patients with inadequate RA response. EOT End of treatment, Infliximab-EU Infliximab sourced from the European Union, RA Rheumatoid arthritisBack to article page