Fig. 2

Quantitative RT-PCR analysis for TGFβ, IL-1β, CXCR2, CD86, COL I, αSMA, S100A4, CXCR4, and CD11a gene expression in cultures of systemic sclerosis (SSc) and healthy subject (HS) fibrocytes after 3 h of CTLA4-Ig treatment. Quantitative RT-PCR analysis for TGFβ, IL-1β, CXCR2, CD86, COL I, αSMA, S100A4, CXCR4, and CD11a gene expression in cultures of SSc fibrocytes (a) and HS fibrocytes (b) either untreated (CNT) or treated for 3 h with CTLA4-Ig at various doses (10, 50, 100, and 500 μg/ml). *p < 0.05, **p < 0.01