Table 2 Clinical characteristics at index date
Knee replacement | ||
|---|---|---|
Case (n = 218) | Control (n = 540) | |
(n = 204) | (n = 537) | |
BMI ≥ 27 kg/m2, % (n) | 75.0% (153) | 70.6% (379) |
WOMAC, median (IQR) | ||
Pain (0–20) | 6.0 (4.0–9.0) | 5.0 (3.0–8.0) |
Function (0–68) | 22.2 (14.9–31.0) | 18.0 (8.5–25.5) |
Stiffness (0–10) | 3.0 (2.0–4.0) | 3.0 (2.0–4.0) |
Total (0–98) | 31.2 (21.8–43.0) | 25.0 (13.0–37.0) |
KOOS, median (IQR) | ||
Pain (0–100) | 61.1 (47.2–72.2) | 66.7 (55.6–79.3) |
Symptoms (0–100) | 64.3 (50.0–78.6) | 75.0 (58.9–85.7) |
QoL (0–100) | 43.8 (31.3–56.3) | 56.3 (43.8–68.8) |
Kellgren-Lawrence grade, % (n) | ||
0 | 1.4% (3) | 1.7% (9) |
1 | 3.7% (8) | 3.7% (20) |
2 | 19.3% (42) | 23.9% (129) |
3 | 31.6% (69) | 29.8% (161) |
4 | 44.0% (96) | 40.9% (221) |
(n = 211) | (n = 524) | |
JSW (mm), median (IQR) | 2.0 (0.8–4.6) | 2.8 (1.1–4.6) |
Cartilage volume (mm3), median (IQR) | (n = 201) | (n = 510) |
Global knee | 11,037 (9127 - 13,634) | 11,058 (9351 - 13,508) |
Medial compartment | 5127 (3971 - 6482) | 5219 (4176 - 6502) |
Lateral compartment | 6028 (4864 - 7480) | 6043 (4970 - 7265) |
BML | (n = 201) | (n = 511) |
Global | ||
Median (IQR) | 2.0 (0.6–4.4) | 1.7 (0.4–3.8) |
BML ≥ 1%, % (n) | 65.7% (132) | 61.5% (314) |
Medial compartment | ||
Median (IQR) | 0.014 (0.0–0.058) | 0.021 (0.0–0.057) |
BML ≥ 1%, % (n) | 34.9% (76) | 42.2% (228) |
Lateral compartment | ||
Median (IQR) | 0.005 (0.0–0.025) | 0.0 (0.0–0.018) |
BML ≥ 1%, % (n) | 23.9% (52) | 20.7% (112) |
(n = 215) | (n = 532) | |
Meniscal extrusion, % (n) | 39.5% (85) | 38.5% (205) |