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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion

Fig. 3

The expression of proinflammatory mediators blocking ADAM-17 in RA FLSs. a ADAM-17 siRNA inhibited ADAM-17 expression in RA FLSs. b The expression of fractalkine/CX3CL1 was significantly decreased in TNF-α-stimulated ADAM-17 siRNA-transfected RA FLS-conditioned medium compared with TNF-α-stimulated control siRNA-transfected RA FLS-conditioned medium. (n = number of replicates). ADAM a disintegrin and metalloprotease family protein, FLSs fibroblast-like synoviocytes, siRNA small interfering RNA

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Arthritis Research & Therapy

ISSN: 1478-6362

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