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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion

Fig. 4

Blocking ADAM-17 in RA FLSs reduces THP-1 adhesion. a THP-1 adhesion to ADAM-17 siRNA-transfected RA FLSs was significantly decreased compared with that to control siRNA-transfected RA FLSs. b ICAM-1 on TNF-α-stimulated ADAM-17 siRNA-transfected RA FLSs was significantly decreased compared with that on control siRNA-transfected RA FLSs. (n = number of replicates). ADAM a disintegrin and metalloprotease family protein, RA rheumatoid arthritis, siRNA small interfering RNA

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Arthritis Research & Therapy

ISSN: 1478-6362

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