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Table 1 Summary of patient characteristics (mean ± SE)

From: ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion

 

RA

(n = 23)

OA

(n = 16)

Healthy control

(n = 7)

Age

56.6 ± 3.4

64.2 ± 6.2

46 ± 4.6

Female, n (%)

17 (74)

13 (81)

3 (43)

Methotrexate dose (mg/week)

7.9 ± 1.2

  

Glucocorticoid dose (mg/day)

1.33 ± 0.5

  

DAS28 (ESR)

4.81 ± 0.3

  

Duration (years)

5.2 ± 1.0

  

RF positive (%)

78.3

  

ACPA positive (%)

65.2

  

Stage (I/II/III/IV)

(7/8/4/4)

  

Number of previous biologics

1.0 ± 0.3

  
  1. ACPA anti-citrullinated protein antibodies, DAS28 disease activity score 28, ESR erythrocyte sedimentation rate, ICAM-1 intercellular adhesion molecule 1, RF rheumatoid factor