Table 2 Immunohistochemical staining results in the three patient groups (mTOR, PTEN, and TGF-β1 in acinus)
Negative | Mild positivity | Moderate positivity | Strong positivity | ||
|---|---|---|---|---|---|
mTOR | SS | 3 (6) | 25 (46) | 20 (37) | 6 (11) |
Overlap syndrome | 0 | 11 (55) | 9 (45) | 0 | |
SSc | 1 (9) | 4 (36) | 5 (46) | 1 (9) | |
PTEN | SS | 6 (13) | 23 (49) | – | 18 (38) |
Overlap syndrome | 8 (42) | 5 (26) | – | 6 (32) | |
SSc | 0 | 7 (58) | – | 5 (42) | |
TGF-β1 | SS | 23 (42) | 20 (36) | 10 (18) | 2 (4) |
Overlap syndrome | 3 (14) | 10 (48) | 4 (19) | 4 (19) | |
SSc | 3 (27) | 2 (18) | 1 (9) | 5 (46) |