Fig. 6From: NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritisComparison of plasma OLT1177 levels in mice and humans. a Mean ± SEM of OLT1177 resting plasma level (μg/ml) of mice fed for 3 weeks with standard and OLT1177-enriched diets (n = 5). b Mean ± SEM of maximum concentration (Cmax) of resting plasma levels of OLT1177 in healthy human subjects following a single dose (n = 5) and after eight daily oral doses (n = 5) of OLT1177 (16 mg/kg). Figure 6b is adapted from [16]Back to article page