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Table 4 Effect of bisphosphonates and TNFi, respectively, on spinal radiographic progression in propensity score-adjusted logistic regression analyses

From: A five-year prospective study of spinal radiographic progression and its predictors in men and women with ankylosing spondylitis

  Progression ≥ 2 mSASSS units New syndesmophytes
OR (95% CI) p value OR (95% CI) p value
Exposure to bisphosphonates 2.47 (0.89 to 6.86) 0.083 2.96 (1.02 to 8.62) 0.046
Propensity score, 0–1 0.32 (0.03 to 3.65) 0.36 0.41 (0.03 to 5.59) 0.51
Exposure to TNFi 0.91 (0.40 to 2.08) 0.83 1.05 (0.43 to 2.52) 0.92
Propensity score, 0–1 6.26 (0.78 to 49.89) 0.084 1.18 (0.12 to 11.30) 0.89
TNFi for ≥ 2 years 0.86 (0.35 to 2.09) 0.73 0.81 (0.30 to 2.21) 0.68
Propensity score, 0–1 3.78 (0.41 to 34.593) 0.24 0.69 (0.06 to 8.46) 0.77
  1. Significant p value is shown in bold typeface
  2. mSASSS modified Stoke Ankylosing Spondylitis Spinal Score, TNFi tumor necrosis factor inhibitor