Table 4 Effect of bisphosphonates and TNFi, respectively, on spinal radiographic progression in propensity score-adjusted logistic regression analyses
Progression ≥ 2 mSASSS units | New syndesmophytes | |||
|---|---|---|---|---|
OR (95% CI) | p value | OR (95% CI) | p value | |
Exposure to bisphosphonates | 2.47 (0.89 to 6.86) | 0.083 | 2.96 (1.02 to 8.62) | 0.046 |
Propensity score, 0–1 | 0.32 (0.03 to 3.65) | 0.36 | 0.41 (0.03 to 5.59) | 0.51 |
Exposure to TNFi | 0.91 (0.40 to 2.08) | 0.83 | 1.05 (0.43 to 2.52) | 0.92 |
Propensity score, 0–1 | 6.26 (0.78 to 49.89) | 0.084 | 1.18 (0.12 to 11.30) | 0.89 |
TNFi for ≥ 2 years | 0.86 (0.35 to 2.09) | 0.73 | 0.81 (0.30 to 2.21) | 0.68 |
Propensity score, 0–1 | 3.78 (0.41 to 34.593) | 0.24 | 0.69 (0.06 to 8.46) | 0.77 |