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Table 1 Characteristics of patients with SLE by disease activity status

From: Cytokine profiling in active and quiescent SLE reveals distinct patient subpopulations

 

SLE (n = 96)

Healthy subject (n = 13)

p value

Age (years)

50.7 (43.9, 58.8)

40.0 (31.5, 48.5)

0.012

Gender (female)

95 (99.0%)

12 (92.3%)

0.626

Ethnicity

  

1.000

 Caucasian

74 (77.1%)

13 (100%)

 

 Black Caribbean

6 (6.3%)

 

 Black African

3 (3.1%)

 

 Indian

2 (2.1%)

 

 Pakistani

3 (3.1%)

 

 Chinese

1 (1.0%)

 

 Other

3 (3.1%)

 

Disease duration (years)

11.7 (6.84, 21.4)

≥ 4 ACR criteria

82 (85.4%)

ACR criteria

  

 Malar rash

54 (56.3%)

  

 Discoid rash

16 (16.7%)

 

 Photosensitivity

60 (62.5%)

 

 Oral ulcers

54 (56.3%)

 

 Arthritis

62 (64.6%)

 

 Serositis

32 (33.3%)

 

 Renal

26 (27.1%)

 

 Neurological

10 (10.4%)

 

 Haematological

57 (59.4%)

 

 Immunological

48 (50.0%)

 

 ANA

82 (85.4%)

 

Oral prednisolone use

41/93 (44.1%)

 

Antimalarial use

66/93 (71.0%)

 

Immunosuppressant use

32/92 (34.8%)

 
  1. Results show the number (percentage) or median (IQR) values. The Mann-Whitney U test or Fisher’s exact test was used to compare values in the active and the inactive groups
  2. SLE systemic lupus erythematosus, ACR American College of Rheumatology, ANA antinuclear antibody