The relationship between ferritin and urate levels and risk of gout

Table 3 Association of serum ferritin, CRP and serum urate with gout flares/year

Population	Ferritin (ng ml^− 1)				C-reactive protein (mg dl^− 1)		Serum urate (mg dl^− 1)
Population	β (95% CI)^a	p ^a	β (95% CI)^b	p ^b	β (95% CI)^a	p ^a	β (95% CI)^a	p ^a
NZ European	0.09 (0.003; 0.17)	0.042	0.069 (− 0.01; 0.14)	0.067	1.75 (− 3.85; 7.37)	0.54	− 0.61 (− 1.48; 0.25)	0.16
NZ Polynesian	− 0.11 (− 0.24; 0.03)	0.14	−0.091 (− 0.22; 0.03)	0.15	−9.95 (− 23.75; 3.84)	0.16	−1.59 (− 3.88; 0.71)	0.17
US	0.02 (0.01; 0.04)	0.002	0.018 (0.001; 0.04)	0.043	0.10 (− 0.13; 0.35)	0.38	0.13 (− 0.04; 0.30)	0.13

Values represent change in the annual frequency of flares per 10 ng ml^− 1 increase in serum ferritin. Levels of urate are at the time of subject recruitment
CRP C-reactive protein, CI confidence interval, NZ New Zealand, US United States
^aAdjusted for age, body mass index and number of self-reported Polynesian grandparents in the NZ Polynesian analyses
^bAdditionally adjusted for allopurinol usage

ISSN: 1478-6362