Outcome domain | Outcome variable | No. of subjects | Pearson’s correlation (unadjusted) | Partial correlation (BMI and age-adjusted) | ||||
---|---|---|---|---|---|---|---|---|
r | (95% CI) | p Value | r | (95% CI) | p Value | |||
Performance-Based Function | Endurance (6MWT, ft) | 159 | 0.43 | (0.30, 0.55) | < 0.001 | 0.28 | (0.12, 0.41) | < 0.001 |
Strength (5TSTS time, s) (ln) | 156 | − 0.17 | (− 0.32, − 0.01) | 0.01 | − 0.02 | (− 0.18, 0.14) | 0.81 | |
Self-reported function | PROMIS PF | 159 | 0.25 | (0.09, 0.39) | 0.002 | 0.15 | (− 0.01, 0.30) | 0.07 |
SF-36 PF | 160 | 0.31 | (0.15, 0.43) | < 0.001 | 0.20 | (0.06, 0.38) | 0.01 | |
Pain | Resting pain (0–10) | 171 | − 0.04 | (− 0.19, 0.11) | 0.61 | 0.02 | (− 0.14, 0.18) | 0.80 |
Movement pain (6MWT) | 160 | − 0.09 | (− 0.24, 0.07) | 0.28 | − 0.01 | (− 0.17, 0.14) | 0.87 | |
Movement pain (5TSTS) | 159 | − 0.04 | (− 0.19, 0.12) | 0.65 | − 0.00 | (− 0.16, 0.16) | 0.98 | |
BPI severity | 160 | 0.00 | (− 0.16, 0.16) | 0.99 | 0.01 | (− 0.14, 0.17) | 0.87 | |
BPI interference | 160 | − 0.05 | (− 0.20, 0.11) | 0.52 | − 0.02 | (− 0.17, 0.14) | 0.84 | |
Pain sensitivity | PPT cervical (ln) | 159 | − 0.10 | (− 0.25, 0.06) | 0.21 | − 0.08 | (− 0.24, 0.08) | 0.31 |
PPT lumbar (ln) | 159 | − 0.04 | (− 0.19, 0.12) | 0.65 | − 0.03 | (− 0.19, 0.13) | 0.70 | |
PPT leg (ln) | 159 | 0.01 | (− 0.16, 0.15) | 0.92 | 0.01 | (− 0.16, 0.15) | 0.88 | |
CPM lumbar (%) | 138 | 0.14 | (− 0.03, 0.30) | 0.10 | 0.14 | (− 0.04, 0.30) | 0.12 | |
CPM leg (%) | 134 | 0.07 | (− 0.11, 0.23) | 0.45 | 0.11 | (− 0.06, 0.28) | 0.21 | |
Fatigue | Resting fatigue (0–10) | 171 | − 0.11 | (− 0.25, 0.05) | 0.17 | − 0.01 | (− 0.17, 0.14) | 0.86 |
Movement fatigue (6MWT) | 160 | − 0.20 | (− 0.35, − 0.05) | 0.01 | − 0.20 | (− 0.35, −0.05) | 0.01 | |
Movement fatigue (5TSTS) | 160 | 0.00 | (− 0.15, 0.16) | 0.96 | − 0.02 | (− 0.18, 0.14) | 0.81 | |
Multidimensional (MAF) | 159 | − 0.05 | (− 0.21, 0.11) | 0.52 | − 0.05 | (− 0.20, 0.11) | 0.58 | |
Psychological constructs | Pain Catastrophizing (Pain Catastrophizing Scale) | 160 | 0.05 | (− 0.10, 0.21) | 0.52 | 0.01 | (− 0.15, 0.16) | 0.93 |
Fear of movement (TSK) | 160 | − 0.01 | (− 0.17, 0.14) | 0.89 | − 0.01 | (− 0.17, 0.15) | 0.89 | |
Disease impact | FIQR total | 171 | − 0.12 | (− 0.27, 0.03) | 0.12 | − 0.10 | (− 0.25, 0.06) | 0.24 |
Quality of life | Physical (SF-36 PCS) | 158 | 0.27 | (0.11, 0.41) | 0.001 | 0.22 | (0.06, 0.37) | 0.006 |
Emotional (SF-36 MCS) | 158 | − 0.01 | (− 0.17, 0.14) | 0.89 | − 0.01 | (− 0.17, 0.16) | 0.99 |