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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis

Fig. 6

Imaging of apoptotic cells with 99mTc-rhAnnexin V-128 in fos-related antigen 2 (Fra-2) transgenic (tg) mice. a Ex vivo autoradiography for 99mTc-rhAnnexin V-128 in the lungs of Fra-2 tg mice versus wild-type mice. Frozen lung sections derived from a Fra-2-tg mouse and a wild-type mouse showed higher accumulation of 99mTc-rhAnnexin V-128 (1 h post injection (p.i.)) in lungs of transgenic mice. b In vivo single photon emission computed tomography (SPECT/CT) of 99mTc-rhAnnexin V-128 (4 h p.i.) administrated to Fra-2 tg mice and wild-type littermates at age 19 weeks. Herein, the chest cavity including the heart and the lungs is shown

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