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Table 1 Fibrotic lung remodeling according to the Ashcroft score [22]

From: Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis

Grade of fibrosis Histological changes
0 Normal lung
1 Minimal fibrous thickening of alveolar/bronchial walls
2 Intermediary stage between 1 and 3
3 Moderate thickening of walls without obvious damage to the lung architecture
4 Intermediary stage between 3 and 5
5 Increased fibrosis with definite damage to lung structure and formation of fibrous bands or small fibrous masses
6 Intermediary stage between 5 and 7
7 Severe distortion of structure and large fibrous areas; honeycombing lung is placed in this category
8 Total fibrous obliteration of the field