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Table 1 Fibrotic lung remodeling according to the Ashcroft score [22]

From: Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis

Grade of fibrosis

Histological changes

0

Normal lung

1

Minimal fibrous thickening of alveolar/bronchial walls

2

Intermediary stage between 1 and 3

3

Moderate thickening of walls without obvious damage to the lung architecture

4

Intermediary stage between 3 and 5

5

Increased fibrosis with definite damage to lung structure and formation of fibrous bands or small fibrous masses

6

Intermediary stage between 5 and 7

7

Severe distortion of structure and large fibrous areas; honeycombing lung is placed in this category

8

Total fibrous obliteration of the field