Variable | AS (n = 125) |
---|---|
Men/women, n | 78/47 |
Age at time of study (years), mean ± SD | 48.3 ± 9.6 |
Age at time of diagnosis (years), mean ± SD | 39.5 ± 9.6 |
HLA-B27 positive, n (%) | 92 (74.8) |
Syndesmophytes, n (%) | 51 (41.5) |
History of synovitis, n (%) | 35 (28.0) |
History of enthesitis, n (%) | 45 (36.0) |
Extra-articular manifestations, n (%) | 38 (30.4) |
Psoriasis | 12 (9.6) |
Inflammatory bowel disease | 10 (8.0) |
Uveitis | 22 (17.6) |
Therapy with TNF inhibitors, n (%) | 49 (39.8) |
ASDAS, mean ± SD | 2.4 ± 0.9 |
BASFI, mean ± SD | 3.9 ± 2.5 |
BASMI, mean ± SD | 3.2 ± 1.7 |
MASES, median (IQR) | 1 (0.0–4.0) |
BASDAI, mean ± SD | 3.7 ± 2.0 |
CRP (mg/l), median (IQR) | |
At time of study | 5.2 ± 6.7 |
At time of disease diagnosis | 10.8 ± 19.0 |
CRP > 3 mg/L at time of disease diagnosis, n (%) | 72 (57.6) |
ESR (mm/1st hour), median (IQR) | |
At time of study | 12.4 ± 13.4 |
At time of disease diagnosis | 16.1 ± 15.9 |
History of classic cardiovascular risk factors, n (%) | |
Current smokers | 37 (29.6) |
Ex-smokers | 31 (24.8) |
Obesity | 23 (18.4) |
Dyslipidemia | 40 (32.0) |
Hypertension | 21 (16.8) |
Blood pressure (mmHg), mean ± SD | |
Systolic | 130.6 ± 15.3 |
Diastolic | 79.5 ± 9.7 |
Cholesterol and triglycerides (mg/dl), mean ± SD | |
Total cholesterol | 200.7 ± 34.5 |
HDL cholesterol | 55.6 ± 14.8 |
LDL cholesterol | 124.6 ± 31.7 |
Triglycerides | 97.3 ± 49.4 |
Carotid plaques, n (%) | 55 (44.0) |
Aortic calcification, n (%) | 28 (22.4) |
TC-SCORE ≥ 5, n (%) | 7 (5.6) |