Fig. 4From: Tofacitinib inhibits granulocyte–macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophilsCaspase-1 expressions in granulocyte–macrophage colony-stimulating factor (GM-CSF)-treated neutrophils. Neutrophils were treated with GM-CSF (10 ng/mL) in the presence or absence of tofacitinib for 12 h. Cellular lysates were analyzed by Western blotting by using anti-caspase-1 or anti-β-actin antibodies. Data are representative of two independent experiments. Abbreviation: MW molecular weightBack to article page