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Table 1 Skin thickness assessed by HFU in patients with SSc and healthy controls

From: High-frequency ultrasound of the skin in systemic sclerosis: an exploratory study to examine correlation with disease activity and to define the minimally detectable difference

  SSc (skin thickness, mm, n = 31) Ctrl (skin thickness, mm, n = 31) P Range
Forearm 1.70(0.40) 1.36 ± 0.19 < 0.001* 0.74–2.40 0.95–1.80
Hand 1.50(0.50) 1.20(0.20) < 0.001* 0.90–2.00 0.79–1.50
Phalanx 1.60(0.30) 1.20(0.15) < 0.001* 1.10–2.00 0.90–1.40
Leg 1.40(0.50) 1.40(0.30) 0.208 0.89–2.50 0.90–1.40
Chest 1.80(0.70) 1.50(0.50) 0.028* 1.10–2.50 1.10–1.60
TST 7.89 ± 1.20 6.61 ± 0.61 < 0.001* 5.47–10.70 5.47–7.70
  1. HFU high-frequency ultrasound, SSc systemic sclerosis, Ctrl controls TST total skin thickness
  2. *Compared with the healthy controls, P < 0.05