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Table 1 Skin thickness assessed by HFU in patients with SSc and healthy controls

From: High-frequency ultrasound of the skin in systemic sclerosis: an exploratory study to examine correlation with disease activity and to define the minimally detectable difference

 

SSc (skin thickness, mm, n = 31)

Ctrl (skin thickness, mm, n = 31)

P

Range

Forearm

1.70(0.40)

1.36 ± 0.19

< 0.001*

0.74–2.40

0.95–1.80

Hand

1.50(0.50)

1.20(0.20)

< 0.001*

0.90–2.00

0.79–1.50

Phalanx

1.60(0.30)

1.20(0.15)

< 0.001*

1.10–2.00

0.90–1.40

Leg

1.40(0.50)

1.40(0.30)

0.208

0.89–2.50

0.90–1.40

Chest

1.80(0.70)

1.50(0.50)

0.028*

1.10–2.50

1.10–1.60

TST

7.89 ± 1.20

6.61 ± 0.61

< 0.001*

5.47–10.70

5.47–7.70

  1. HFU high-frequency ultrasound, SSc systemic sclerosis, Ctrl controls TST total skin thickness
  2. *Compared with the healthy controls, P < 0.05