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Table 2 Clinical profiles of patients with SSc with TST higher and lower than the cutoff in ROC analysis

From: High-frequency ultrasound of the skin in systemic sclerosis: an exploratory study to examine correlation with disease activity and to define the minimally detectable difference

Feature Elevated TST (n = 24) Normal TST (n = 7) P
Male/female 4/20 0/7 0.247
Age (years) 50.21 ± 14.01 37.00 ± 11.02 0.187
Duration 24.00 (26.40) 56.06 ± 30.17 0.002*
DAI 5.24 ± 2.36 1.84 (1.92) 0.048*
mRSS 10.00 (6.00) 4.00 (5.00) 0.031*
RP 21 7 0.325
ILD 16 1 0.014*
PAH 5 3 0.214
DU 4 2 0.483
Muscular involvement 5 3 0.214
Synovitis 10 2 0.531
Scl-70(+) 10 3 0.955
CRP (mg/L) 8.60 (10.48) 3.52 (4.93) 0.038*
ESR (mm/h) 23.00 (16.25) 48.71 ± 43.19 0.723
  1. SSc systemic sclerosis, TST total skin thickness, DAI European Scleroderma Trial and Research group Disease Activity Index, RP Raynaud’s phenomenon, ILD interstitial lung disease, PAH pulmonary artery hypertension, DU digital ulcers, CRP C-reactive protein, ESR erythrocyte sedimentation rate
  2. *P < 0.05