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Table 2 Genes expressed significantly higher in CD8+ T cells of patients with polymyositis than in those with dermatomyositis

From: T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients

Gene symbol

Gene name

TRBV28

T cell receptor beta variable 28

RP3-477M7.5

 

TMIGD2

Transmembrane and immunoglobulin domain containing 2

KLF13

Kruppel like factor 13

CA6

Carbonic anhydrase 6

TMTC1

Transmembrane and tetratricopeptide repeat containing 1

LINC00402

Long intergenic non-protein coding RNA 402

TRBV30

T cell receptor beta variable 30 (gene/pseudogene)

IL6R

Interleukin 6 receptor

EPHA1

EPH receptor A1

XKR9

XK related 9

GABPB1-AS1

GABPB1 antisense RNA 1

LAPTM4B

Lysosomal protein transmembrane 4 beta

EPHA1-AS1

EPHA1 antisense RNA 1

CAMSAP2

Calmodulin regulated spectrin associated protein family member 2

AC012636.1

Uncharacterized LOC101929215

RP11-28F1.2

 

CHMP7

Charged multivesicular body protein 7

SYNJ2

Synaptojanin 2

KLHL6

Kelch like family member 6

PRKCQ-AS1

PRKCQ antisense RNA 1

CASP10

Caspase 10

TXK

TXK tyrosine kinase

CD27

CD27 molecule

TBC1D4

TBC1 domain family member 4

CLN5

CLN5, intracellular trafficking protein

JAML

Junction adhesion molecule like

FAM153A

Family with sequence similarity 153 member A

TNFRSF10D

TNF receptor superfamily member 10d

DHX32

DEAH-box helicase 32 (putative)

STRBP

Spermatid perinuclear RNA binding protein

AL034550.2

Uncharacterized LOC101929698

DGKA

Diacylglycerol kinase alpha

COX10-AS1

COX10 antisense RNA 1

GCSAM

Germinal center associated signaling and motility

SLC7A6

Solute carrier family 7 member 6

ACSL6

Acyl-CoA synthetase long chain family member 6

AKAP7

A-kinase anchoring protein 7

AP005131.6

 

UXS1

UDP-glucuronate decarboxylase 1

PAX8-AS1

PAX8 antisense RNA 1

C21orf33

Chromosome 21 open reading frame 33

RP11-65I12.1

 

GSTM1

Glutathione S-transferase mu 1

  1. The table demonstrates the genes that overlap between the two analytical stages and have a significantly higher expression in CD8+ T cells of patients with polymyositis than in those with dermatomyositis. A false discovery rate threshold of 5% based on the method of Benjamini-Hochberg was used to identify significant differentially expressed genes