Skip to main content
Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Immune complexes containing scleroderma-specific autoantibodies induce a profibrotic and proinflammatory phenotype in skin fibroblasts

Fig. 7

tlr mRNA expression levels in fibroblasts stimulated with SSc-ICs or control NHS-ICs. Fibroblasts exposed to SSc-ICs or NHS-ICs (1:2 dilution). Poly(I:C) and LPS, at concentration of 1 μg/ml, used as controls. a tlr2; b tlr3; c tlr4; d tlr9. **p < 0.001, ***p < 0.0001 versus medium. ACA anti-centromeric protein antibodies, anti-Th/To anti-Th/To antibodies, ARA anti-RNA polymerase III antibodies, ATA anti-DNA topoisomerase I antibodies, IC immune complex, LPS lipopolysaccharide, NHS normal healthy subjects, poly(I:C) polyinosinic-polycytidylic acid, TLR Toll-like receptor

Back to article page