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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Enhanced IL-6/phosphorylated STAT3 signaling is related to the imbalance of circulating T follicular helper/T follicular regulatory cells in patients with rheumatoid arthritis

Fig. 2

Expression of programmed death-1 (PD-1), ICOS, intracellular IL-21 or pSTAT3 in circulating CD4+CXCR5+ follicular helper T (Tfh) cells of patients with rheumatoid arthritis (RA) and the healthy controls (HCs). Horizontal bars indicate the mean and error bars represent the SEM. The expression of PD-1 (a), inducible co-stimulator (ICOS) (b), intracellular IL-21 (c) or phosphorylated STAT3 (pSTAT3) (d) was investigated gating on CD4+CXCR5+ T cells in patients with active RA (circles), patients with inactive RA (squares), and the HCs (triangles)

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