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Table 1 Participant baseline characteristics

From: The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated vasculitis

 

AAV (n = 53)

HV (n = 30)

Age, years

69.0 [62.8–75.3]

70.5 [66.8–74.0]*

Gender, male:female

35:18

14:16*

ANCA specificity, PR3:MPO

34:18

–

AAV disease chronicity, years

6.0 [3.2–12.0]

–

Renal function eGFR, mL/min per 1.73 m2

53 [21]

–

Urine albumin-to-creatinine ratio, mg/mmol

4.4 [1.4–9.9]

–

Steroids, n (%)

39 (73.6)

–

Mycophenolate mofetil, n (%)

14 (26.4)

–

Azathioprine, n (%)

19 (35.8)

–

No current immunosuppression, n (%)

4 (7.5)

–

Ever smoker, n (%)

26 (49.1)

–

Diabetes mellitus, n (%)

11 (20.8)

–

On statin treatment, n (%)

29 (54.7)

 
  1. Data are displayed as median [interquartile range] apart from renal function displayed as mean [standard deviation]. Immunosuppressive treatment refers to number and percentage of patients on the respective immunosuppressive agent at the time of study entry.
  2. *Comparison between ANCA-associated vasculitis (AAV) and healthy volunteers (HV): age (Mann–Whitney U test, P = 0.557), gender (Fisher’s exact, P = 0.106)
  3. Abbreviations: eGFR estimated glomerular filtration rate, MPO myeloperoxidase, PR3 proteinase 3