Skip to main content

Table 1 Participant baseline characteristics

From: The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated vasculitis

  AAV (n = 53) HV (n = 30)
Age, years 69.0 [62.8–75.3] 70.5 [66.8–74.0]*
Gender, male:female 35:18 14:16*
ANCA specificity, PR3:MPO 34:18
AAV disease chronicity, years 6.0 [3.2–12.0]
Renal function eGFR, mL/min per 1.73 m2 53 [21]
Urine albumin-to-creatinine ratio, mg/mmol 4.4 [1.4–9.9]
Steroids, n (%) 39 (73.6)
Mycophenolate mofetil, n (%) 14 (26.4)
Azathioprine, n (%) 19 (35.8)
No current immunosuppression, n (%) 4 (7.5)
Ever smoker, n (%) 26 (49.1)
Diabetes mellitus, n (%) 11 (20.8)
On statin treatment, n (%) 29 (54.7)  
  1. Data are displayed as median [interquartile range] apart from renal function displayed as mean [standard deviation]. Immunosuppressive treatment refers to number and percentage of patients on the respective immunosuppressive agent at the time of study entry.
  2. *Comparison between ANCA-associated vasculitis (AAV) and healthy volunteers (HV): age (Mann–Whitney U test, P = 0.557), gender (Fisher’s exact, P = 0.106)
  3. Abbreviations: eGFR estimated glomerular filtration rate, MPO myeloperoxidase, PR3 proteinase 3