SU at baseline, μmol/L
|
Time period from baseline screening to 1998
|
Time period from 1998 to end of study
|
---|
Incident gout (n)
|
Person-years at risk
|
Inc. (95% CI)*
|
HR unadjusted (95%CI)
|
HR age adjusted (95%CI)
|
Incident gout (n)
|
Person-years at risk
|
Inc. (95% CI)*
|
HR un-adjusted (95%CI)
|
HR age adjusted (95%CI)
|
---|
Men
|
≤ 360
|
8
|
322,368
|
2.5 (1.1–4.9)
|
1
|
1
|
447
|
188,039
|
237.7 (216.2–260.8)
|
1
|
1
|
361–405
|
7
|
63,617
|
11.0 (4.4–22.7)
|
4.4 (1.6–12.2)
|
4.4 (1.6–12.2)
|
227
|
35,336
|
642.4 (561.5–731.67)
|
2.7 (2.3–3.2)
|
2.7(2.3–3.2)
|
> 405
|
31
|
41,172
|
75.3 (51.2–106.9)
|
30.2 (13.9–65.8)
|
28.6 (13.1–62.3)
|
292
|
19,714
|
1481 (1316–1661)
|
6.5 (5.6–7.5)
|
6.4 (5.6–7.5)
|
Women
|
≤ 360
|
1
|
143,968
|
0.7 (0.009–0.4)
|
n.a.
|
n.a.
|
200
|
137,282
|
145.7 (126.2–167.3)
|
1
|
1
|
361–405
|
2
|
4026
|
49.7 (5.6–179.3)
|
n.a.
|
n.a.
|
25
|
3735
|
669.3 (433.1–981.1)
|
4.7(3.1–7.2)
|
4.4 (2.9–6.7)
|
> 405
|
3
|
2048
|
146.5 (29.5–428)
|
n.a.
|
n.a.
|
29
|
1589
|
1825 (1222–2621)
|
14.0 (9.4–20.6)
|
13.1 (8.8–19.4)
|
- *Per 100,000 person-years at risk