Fig. 2

RORα expression in the labial salivary glands (LSGs) of patients with primary Sjögren’s syndrome (pSS) increased with increasing focus score (FS). a Focal index of all patients with pSS (n = 34) and the statistical analysis: 85.3% (n = 29) of pSS in our study had obvious local lymphocytic sialadenitis (FS > =1). b Expression of RORα expression (green) in LSG sections from patients with pSS with a FS of 0 (n = 5, lower panel) was still higher than in patients without pSS (normal control (NC) (n = 10, upper panel) assessed by indirect immunofluorescence. c RORα expression in patients with pSS with a different FS (n = 29) assessed by indirect immunofluorescence analysis suggested that the RORα expression in the LSGs in pSS increased with increasing FS. Diamidino-phenyl-indole (DAPI) staining for nuclei (blue). Scale bars = 100 μm