Fig. 4
From: The role of RORα in salivary gland lesions in patients with primary Sjögren’s syndrome
Higher expression of IL-17RA in the labial salivary glands (LSGs) of patients with primary Sjögren’s syndrome (pSS). a Protein expression level of IL-17R (96 kD) in LSGs. Expression of IL-17R in tissue with pSS (n = 6) was higher compared with normal control (NC) (n = 4). b Immunohistochemical analysis of local IL-17R in patients with pSS (n = 34) and NC (n = 10) LSGs. IL-17R-positive cells are significantly more numerous in the LSGs of patients with pSS compared with NC, along with an upward trend as the focus score (FS) increased. Scale bars = 50 μm; insets, × 2 magnification. Abbreviations: A, acinus; Adip, adipocytes; Bv, blood vessel; D, ductus; Ly, lymphocyte infiltration