Fig. 2From: Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized miceChanges in L5 total volume of bone mineral density (BMDtv) and microarchitecture parameters of the trabecular bone determined by micro-CT. a Representative three-dimensional images of trabecular bone. b–i The parameters of L5 trabecular bone. There is markedly decreased BMDtv, bone volume (BV)/total volume (TV), trabecular number (Tb.N; 1/mm), and connectivity density (CONN.D, 1/mm3), and increased trabecular thickness (Tb.Th; mm), and structural model index (SMI) in the ovariectomized (OVX) group when compared with the control (ct) group. Mice were analyzed at 12 weeks post-sham or OVX surgery, n = 6 per group. Data are shown as mean ± SD. *p < 0.05. Tb.Pf trabecular pattern factor, Tb.Sp trabecular separationBack to article page