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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized mice

Fig. 2

Changes in L5 total volume of bone mineral density (BMDtv) and microarchitecture parameters of the trabecular bone determined by micro-CT. a Representative three-dimensional images of trabecular bone. bi The parameters of L5 trabecular bone. There is markedly decreased BMDtv, bone volume (BV)/total volume (TV), trabecular number (Tb.N; 1/mm), and connectivity density (CONN.D, 1/mm3), and increased trabecular thickness (Tb.Th; mm), and structural model index (SMI) in the ovariectomized (OVX) group when compared with the control (ct) group. Mice were analyzed at 12 weeks post-sham or OVX surgery, n = 6 per group. Data are shown as mean ± SD. *p < 0.05. Tb.Pf trabecular pattern factor, Tb.Sp trabecular separation

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