TY - JOUR AU - Hjorton, Karin AU - Hagberg, Niklas AU - Israelsson, Elisabeth AU - Jinton, Lisa AU - Berggren, Olof AU - Sandling, Johanna K. AU - Thörn, Kristofer AU - Mo, John AU - Eloranta, Maija-Leena AU - Rönnblom, Lars AU - The DISSECT consortium PY - 2018 DA - 2018/10/24 TI - Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor JO - Arthritis Research & Therapy SP - 238 VL - 20 IS - 1 AB - In systemic lupus erythematosus (SLE), immune complexes (ICs) containing self-derived nucleic acids trigger the synthesis of proinflammatory cytokines by immune cells. We asked how an interleukin (IL)-1 receptor-associated kinase 4 small molecule inhibitor (IRAK4i) affects RNA-IC-induced cytokine production compared with hydroxychloroquine (HCQ). SN - 1478-6362 UR - https://doi.org/10.1186/s13075-018-1702-0 DO - 10.1186/s13075-018-1702-0 ID - Hjorton2018 ER -