Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 5 Factors associated with positive imaging (MRI-SIJ+ and/or X-SIJ+) in patients with certain diagnosis of axial spondyloarthritis (level of confidence ≥ 7/10)

From: Are gender-specific approaches needed in diagnosing early axial spondyloarthritis? Data from the SPondyloArthritis Caught Early cohort

Independent variables Univariable analysis
N = 289a
Multivariable model
N = 289a
OR (95% CI) p OR (95% CI) p
Male gender 2.0 (1.2, 3.3) 0.007 1.8 (1.0, 3.1) 0.05
Age at CBP onset 1.0 (0.9, 1.0) 0.04 1.0 (0.9, 1.0) 0.052
HLA-B27+ 2.0 (1.2, 3.4) 0.01 1.8 (1.0, 3.3) 0.04
Positive family history of SpAb 0.4 (0.3, 0.7) 0.002 0.4 (0.2, 0.7) 0.001
Elevated CRP/ESR 1.6 (1.0, 2.7) 0.06 1.5 (0.9, 2.7) 0.1
Smoking (N=284c) 1.1 (0.8, 1.6) 0.4 NI -
  1. Data presented as odds ratio (95% confidence interval). Bold data indicate significant results
  2. MRI-SIJ magnetic resonance imaging of sacroiliac joints, X-SIJ plain radiograph of of sacroiliac joints, CBP chronic back pain, HLA human leukocyte antigen, SpA spondyloarthritis, CRP C-reactive protein, ESR erythrocyte sedimentation rate, NI not included in multivariable model because p > 0.1 at univariate analysis and no confounder
  3. aNumber of patients with complete data on all variables
  4. bFamily history of spondyloarthritis according to the Assessment of SpondyloArthritis international Society includes family history in first or second-degree relatives of ankylosing spondylitis, uveitis, reactive arthritis, inflammatory bowel disease, or psoriasis
  5. cSmoking data unavailable in five additional patients