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Table 4 Estimates of haplotype frequencies in patients with fibromyalgia (n = 393) and healthy controls (n = 388)a

From: Association between brain-derived neurotrophic factor gene polymorphisms and fibromyalgia in a Korean population: a multicenter study

Combined allelesa

All subjects

Controls

Fibromyalgia

p valueb

TGACCGCTGC

29.6 ± 0.75

20.22 ± 0.9

38.87 ± 0.88

0.0001

TATCCAACCT

20.16 ± 0.44

12.94 ± 0.57

27.29 ± 0.52

 

TGACCACTGC

14.8 ± 0.75

25.26 ± 0.89

4.47 ± 0.88

 

TAACTACCCT

11.97 ± 0.42

6.99 ± 0.5

16.89 ± 0.53

 

TATCCGACCT

8.94 ± 0.45

15.76 ± 0.59

2.21 ± 0.52

 

TAACTGCCCT

5.74 ± 0.42

9.8 ± 0.5

1.72 ± 0.53

 

CAACCACCGC

3.20 ± 0.17

2.06 ± 0.22

4.33 ± 0.24

 
  1. aData are percentages ± SE
  2. aMissing data were excluded (n = 51). Among 39 haplotype structures, 7 haplotypes with frequency of at least 1% in both the patients and controls are presented
  3. bp values for permutation test of the null hypothesis that cases and controls are random draws from a common set of haplotype frequencies (number of permutations = 10,000)