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Table 5 Combined allele frequencies and odds ratios in patients with fibromyalgia and healthy controlsa

From: Association between brain-derived neurotrophic factor gene polymorphisms and fibromyalgia in a Korean population: a multicenter study

Combined alleles

Controls, n (%)

Fibromyalgia, n (%)

Crude OR (95% CI)

p valueb

Age and sex adjusted OR (95% CI)

p valueb

TGACCGCTGC

193 (26.6)

340 (45)

1.0 (reference)

 

1.0 (reference)

 

TATCCAACCT

119 (16.4)

232 (30.7)

1.107 (0.834–1.469)

0.483

1.106 (0.833–1.47)

0.487

TGACCACTGC

160 (22)

1 (0.1)

0.004 (0–0.026)

< 0.001

0.004 (0.0–0.026)

< 0.001

TAACTACCCT

66 (9.1)

146 (19.3)

1.256 (0.894–1.765)

0.19

1.248 (0.887–1.756)

0.204

TATCCGACCT

103 (14.2)

0 (0)

0 (0-Inf)

0.963

0 (0-Inf)

0.963

TAACTGCCCT

65 (9)

0 (0)

0 (0-Inf)

0.971

0 (0-Inf)

0.97

CAACCACCGC

20 (2.8)

37 (4.9)

1.05 (0.593–1.861)

0.867

1.088 (0.612–1.934)

0.774

  1. Abbreviations: OR odds ratio, CI confidence interval
  2. aMissing data were excluded (n = 51). Among 39 haplotype structures, 7 haplotypes with a frequency of at least 1% in both the patients and controls are presented; the total frequency of the other haplotype structures was 46 (6%) for controls and 30 (3.8%) for patients. Logistic regression models were used to calculate ORs
  3. bComputed for the estimated coefficient of each haplotype in the logistic regression