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Table 5 Combined allele frequencies and odds ratios in patients with fibromyalgia and healthy controlsa

From: Association between brain-derived neurotrophic factor gene polymorphisms and fibromyalgia in a Korean population: a multicenter study

Combined alleles Controls, n (%) Fibromyalgia, n (%) Crude OR (95% CI) p valueb Age and sex adjusted OR (95% CI) p valueb
TGACCGCTGC 193 (26.6) 340 (45) 1.0 (reference)   1.0 (reference)  
TATCCAACCT 119 (16.4) 232 (30.7) 1.107 (0.834–1.469) 0.483 1.106 (0.833–1.47) 0.487
TGACCACTGC 160 (22) 1 (0.1) 0.004 (0–0.026) < 0.001 0.004 (0.0–0.026) < 0.001
TAACTACCCT 66 (9.1) 146 (19.3) 1.256 (0.894–1.765) 0.19 1.248 (0.887–1.756) 0.204
TATCCGACCT 103 (14.2) 0 (0) 0 (0-Inf) 0.963 0 (0-Inf) 0.963
TAACTGCCCT 65 (9) 0 (0) 0 (0-Inf) 0.971 0 (0-Inf) 0.97
CAACCACCGC 20 (2.8) 37 (4.9) 1.05 (0.593–1.861) 0.867 1.088 (0.612–1.934) 0.774
  1. Abbreviations: OR odds ratio, CI confidence interval
  2. aMissing data were excluded (n = 51). Among 39 haplotype structures, 7 haplotypes with a frequency of at least 1% in both the patients and controls are presented; the total frequency of the other haplotype structures was 46 (6%) for controls and 30 (3.8%) for patients. Logistic regression models were used to calculate ORs
  3. bComputed for the estimated coefficient of each haplotype in the logistic regression