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Table 3 Associations between baseline effusion-synovitis/IPFP and increased MRI-detected OPs over 2.6 years

From: MRI-detected osteophytes of the knee: natural history and structural correlates of change

  Multivariable* Multivariable**
RR (95% CI) RR (95% CI)
Increased total MRI-detected OP (yes or no)
 Total effusion-synovitis 1.23 (1.05, 1.45) 1.08 (0.94, 1.24)
 Suprapatellar effusion-synovitis 1.25 (1.09, 1.45) 1.08 (0.92, 1.64)
 Central portion effusion-synovitis 1.11 (0.96, 1.29) 1.06 (0.94, 1.20)
 Posterior femoral recess effusion-synovitis 1.14 (0.97, 1.33) 1.05 (0.93, 1.19)
 Subpopliteal recess effusion-synovitis 1.15 (1.03, 1.29) 1.07 (0.97, 1.18)
 IPFP quality score (0–6) 1.17 (1.10, 1.24) 1.08 (1.01, 1.15)
 IPFP maximum area (cm2) 1.04 (0.93, 1.16) 1.03 (0.93, 1.14)
 IPFP abnormal change (yes/no) 1.21 (0.91, 1.60) 0.91 (0.69, 1.22)
Increased medial MRI-detected OP (yes or no)
 Total effusion-synovitis 1.25 (0.91, 1.73) 1.13 (0.84, 1.51)
 Suprapatellar effusion-synovitis 1.31 (0.96, 1.80) 1.15 (0.89, 1.48)
 Central portion effusion-synovitis 1.14 (0.83, 1.58) 1.02 (0.75, 1.39)
 Posterior femoral recess effusion-synovitis 1.10 (0.83, 1.46) 1.01 (0.76, 1.33)
 Subpopliteal recess effusion-synovitis 1.22 (0.99, 1.52) 1.09 (0.88, 1.34)
 IPFP quality score (0–6) 1.40 (1.24, 1.57) 1.20 (1.06, 1.37)
 IPFP maximum area (cm2) 0.96 (0.77, 1.20) 0.96 (0.78, 1.19)
 IPFP abnormal change (yes/no) 3.17 (1.31, 7.65) 1.87 (0.73, 4.79)
Increased lateral MRI-detected OP (yes or no)
 Total effusion-synovitis 1.40 (1.13, 1.75) 1.27 (1.03, 1.57)
 Suprapatellar effusion-synovitis 1.37 (1.22, 1.68) 1.22 (1.01, 1.47)
 Central portion effusion-synovitis 1.24 (1.00, 1.53) 1.16 (0.97, 1.40)
 Posterior femoral recess effusion-synovitis 1.18 (0.97, 1.43) 1.08 (0.91, 1.28)
 Subpopliteal recess effusion-synovitis 1.12 (0.96, 1.31) 1.08 (0.94, 1.25)
 IPFP quality score (0–6) 1.29 (1.19, 1.40) 1.19 (1.08, 1.30)
 IPFP maximum area (cm2) 1.02 (0.89, 1.18) 1.05 (0.91, 1.21)
 IPFP abnormal change (yes/no) 1.87 (1.15, 3.03) 1.40 (0.87, 2.25)
  1. Dependent variable: increases in magnetic resonance imaging (MRI)-detected osteophytes (OPs) (yes or no). Independent variables: baseline effusion-synovitis
  2. IPFP intrapatellar fat pad
  3. *Adjusted for age, sex and body mass index
  4. **Further adjusted for bone marrow lesions, cartilage defects and baseline OPs. Significant differences are shown in bold