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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Relevance of interferon-gamma in pathogenesis of life-threatening rapidly progressive interstitial lung disease in patients with dermatomyositis

Fig. 3

Histopathological findings from two autopsies. a Case 1: (1, 2) lung; hematoxylin-eosin (H&E) staining; (3, 4) lung, immunostaining for interferon (IFN)-γ; (5, 6) hilar lymph nodes, H&E staining; (7, 8) hilar lymph nodes, immunostaining for IFN-γ; (9, 10) spleen, H&E staining; (11, 12) spleen immunostaining for IFN-γ; (13, 14) lung, immunostaining for interleukin (IL)-6; (15, 16) hilar lymph nodes, immunostaining for IL-6; (17, 18) spleen, immunostaining for IL-6. b Case 2: (1, 2) lung, H&E staining; (3, 4) lung, immunostaining for IFN-γ; (5, 6) hilar lymph nodes, H&E staining; (7, 8) hilar lymph nodes, immunostaining for IFN-γ; (9, 10) spleen, H&E staining; (11, 12) spleen, immunostaining for IFN-γ; (13, 14) lung, immunostaining for IL-6; (15, 16) hilar lymph nodes, immunostaining for IL-6; (17, 18) spleen, immunostaining for IL-6. Red arrows show histiocytes, blue arrows show plasma cells

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