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Table 1 Clinical characteristics of patients

From: Relevance of interferon-gamma in pathogenesis of life-threatening rapidly progressive interstitial lung disease in patients with dermatomyositis

  DM with RP-ILD DM without RP-ILD p value
n 9 10  
Age, years 69.3 ± 3.9 63.9 ± 14.2 0.68
Female (n, %) 8, 88.9 6, 60.0 0.31
Disease duration (months) 18.1 ± 39.8 7.6 ± 8.7 0.40
Smokers (current and past) (%) 11.1 30.0 0.31
Number of GC pulses 2.2 ± 1.1 N/A  
PaO2/FiO2 ratio 160 ± 90 N/A  
Leukocyte count (/μL) 9438 ± 5751 7620 ± 5458 0.35
LDH (U/L) 549 ± 357 376 ± 168 0.27
KL-6 (U/mL) 1087 ± 584 1419 ± 1756 0.46
IgG (mg/dL) 1225 ± 398 1452 ± 454 0.27
Positivity for anti-CADM140/MDA5 Ab (%) 66.7 50.0 0.76
CT score (G) 2.1 ± 0.7 N/A  
CT score (F) 1.2 ± 0.6 N/A  
  1. Data are mean ± SD or number of patients (percentage)
  2. DM dermatomyositis, RP-ILD rapidly progressive-interstitial lung disease, GC glucocorticoid, PaO2/FiO2 partial arterial pressure of oxygen/fraction of inspired oxygen, KL-6 Kerbs von Lungren 6 antigen, CT computed tomograpghy, G ground glass opacity, F fibrosis