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Table 2 Absolute rate of CKD per 10,000 person-years and hazard ratios

From: Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study

Variable

Gout

  

Non-gout

  

Unadjusted

 

Adjusted*

 

n

Rate‡

95% CI

n

Rate‡

95% CI

Hazard ratio

95% CI

Hazard ratio

95% CI

Overall

6694

28.6

27.9, 29.3

3953

15.8

15.3, 16.3

1.79

1.72, 1.86

1.78

1.70, 1.85

Male

4608

23.6

22.9, 24.3

2681

13.0

12.5, 13.5

1.80

1.71, 1.89

1.78

1.69, 1.87

Female

2086

53.8

51.5, 56.1

1272

28.7

27.1, 30.3

1.82

1.70, 1.95

1.79

1.66, 1.93

Age at index in years

 < 55 years

690

5.8

5.4, 6.30

279

2.3

2.1, 2.6

2.52

2.19, 2.89

1.78

1.54, 2.07

 55–65

1581

24.6

23.4, 25.8

844

12.3

11.5, 13.2

1.99

1.83, 2.16

1.76

1.61, 1.92

 65–75

2506

66.2

63.6, 68.8

1498

33.8

32.1, 35.5

1.91

1.79, 2.04

1.87

1.75, 2.00

 > 75

1917

141.0

134.8, 147.5

1332

78.1

74.0, 82.4

1.75

1.63, 1.88

1.71

1.59, 1.84

IMD (quintiles)

 1 (least deprived)

1579

25.6

24.3, 26.9

914

13.9

13.0, 14.8

1.81

1.67, 1.97

1.84

1.69, 2.01

 2

1689

29.2

27.9, 30.7

1008

16.2

15.2, 17.2

1.78

1.65, 1.92

1.79

1.65, 1.94

 3

1439

30.9

29.3, 32.5

831

16.7

15.6, 17.9

1.83

1.68, 1.99

1.77

1.62, 1.94

 4

1143

29.4

27.8, 31.2

698

16.6

15.4, 17.8

1.76

1.60, 1.93

1.78

1.61, 1.97

 5 (most deprived)

841

29.1

27.2, 31.2

501

16.5

15.1, 18.0

1.76

1.57, 1.96

1.67

1.49, 1.88

  1. CKD chronic kidney disease, IMD index of multiple deprivation
  2. *Adjusted for age, gender, body mass index, smoking status, diabetes mellitus, treated hypertension, rheumatoid arthritis, systemic lupus erythematosus, heart failure, IMD, myocardial infraction, cerebrovascular disease, peripheral vascular disease, history of hospitalisation, consultation rates, and non-steroidal anti-inflammatory drug exposure, when not stratified by them, ‡ per 10,000 person-years