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Table 3 Basic characteristics of gout cases by ULT exposure with 1 and 3 years after gout diagnosis

From: Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study

Variable 1-Year landmark 3-Year landmark
Exposed
n = 4198
Unexposed
n = 35,286
Exposed
n = 4793
Unexposed
n = 23,706
N % N % N % N %
Mean age (SD) 58.2 (12.8) 56.3 (13.5) 56.1 (12.1) 55.1 (12.9)
Male 3485 83.0 28,809 81.6 4151 86.6 19,526 82.4
Body mass index
 Normal 530 12.6 6385 18.1 575 12.0 4335 18.3
 Underweight 22 0.5 292 0.8 15 0.3 196 0.8
 Overweight 1504 35.8 13,294 37.7 1781 37.2 9036 38.1
 Obese 1893 45.1 12,801 36.3 2177 45.4 8581 36.2
 Missing 249 5.9 2514 7.1 245 5.1 1558 6.6
Smoking status
 Never/ex-smoker 3808 90.7 30,501 86.4 4355 90.9 20,459 86.3
 Current smoker 390 9.3 4785 13.6 438 9.1 3247 13.7
Comorbidities
 Diabetes mellitus 357 8.5 2114 6.0 338 7.1 1259 5.3
 Treated hypertension 1539 36.7 9509 26.9 1625 33.9 5856 24.7
 Rheumatoid arthritis 40 1.0 213 0.6 39 0.8 122 0.5
 Heart failure 200 4.8 900 2.6 166 3.5 372 1.6
 Myocardial infraction 219 5.2 1247 3.5 216 4.5 685 2.9
 Cerebrovascular disease 176 4.2 1172 3.3 143 3.0 627 2.6
 Peripheral vascular disease 118 2.8 663 1.9 85 1.8 351 1.5
 Anti-diabetic drugs 233 5.6 1462 4.1 208 4.3 860 3.6
 NSAIDs 1082 25.8 4455 12.6 1143 23.8 2887 12.2
 Previous hospitalisations 1256 29.9 8964 25.4 1200 25.0 5392 22.7
IMD quintiles
 1 871 20.7 9211 26.1 1089 22.7 6338 26.7
 2 1021 24.3 8700 24.7 1178 24.6 5894 24.9
 3 889 21.2 7076 20.1 977 20.4 4733 20.0
 4 764 18.2 5935 16.8 827 17.3 3915 16.5
 5 647 15.4 4332 12.3 717 15.0 2810 11.9
Mean serum urate (SD) μmol/L 478.4 (90.8) 432.2 (98.1) 476.5 (95.7) 427.3 (99.1)
Mean serum creatinine (SD)* μmol/L 89.5 (16.7) 87.2 (16.1) 90.3 (15.2) 86.4 (15.4)
  1. NSAID non-steroidal anti-inflammatory drug, IMD Index of multiple deprivation
  2. *Missing serum creatinine value = 10,335 (1-year landmark), 5872 (3-year landmark), missing serum urate: 15,638 (1-year landmark), 10,176 (3-year landmark)