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Table 1 Baseline characteristics of patients with HBsAg/HBcAb+ serostatus

From: Changes in hepatitis B virus surface antibody titer and risk of hepatitis B reactivation in HBsAg-negative/HBcAb-positive patients undergoing biologic therapy for rheumatic diseases: a prospective cohort study

Number of patients

380

Mean age (years)

56.3 ± 12.3

Sex (female)

242 (63.7%)

Number (%) with disease

 Rheumatoid arthritis

272 (71.6%)

 Ankylosing spondylitis

69 (18.2%)

 Psoriasis/psoriatic arthritis

39 (10.3%)

Mean disease duration (years)

 Rheumatoid arthritis (n = 156)

8.7 ± 7.1

 Ankylosing spondylitis (n = 33)

13.3 ± 9.1

 Psoriasis/psoriatic arthritis (n = 24)

11.5 ± 8.8

Number (%) using biologic agents

 Etanercept

124 (32.6%)

 Adalimumab

106 (27.9%)

 Golimumab

63 (16.6%)

 Abatacept

18 (4.7%)

 Tocilizumab

16 (4.2%)

 Rituximab

44 (11.6%)

 Ustekinumab

8 (2.1%)

 Tofacitinib

1 (0.3%)

Number (%) using methotrexate

250 (65.8%)

 Average dose of methotrexate (mg/week)

12.8

Number (%) using glucocorticoids

250 (65.8%)

 Average dose of glucocorticoid (mg/day)

6.3

Number (%) using sulfasalazine

265 (69.7%)

Number (%) using hydroxychloroquine

216 (56.8%)

Number (%) using cyclosporine

81 (21.3%)

  1. HBcAb hepatitis B virus core antibody, HBsAg hepatitis B virus surface antigen