Skip to main content
Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease

Fig. 3

Correlation between cellular and selected serologic/cytokine phenotypes in asymptomatic anti-nuclear antibodies (ANA)+ individuals and patients with systemic autoimmune rheumatic disease (SARD). Spearman correlation matrices for asymptomatic ANA+ individuals (a) and patients with SARD (b). B and T cell populations were gated and defined as outlined in Figs. 1 and 2, plasma cells as outlined in Additional file 1: Figure S3, and CD95+ B cell subpopulations as shown in Additional file 1: Figure S1. The color and size of the dots represents the ρ value, with the scales shown at the bottom of each matrix. Non-significant (p ≥ 0.05) correlation is not displayed. IFN, interferon; BAFF, B cell activating factor

Back to article page