Fig. 6

Effect of miR-29b-1-5p on proinflammatory cytokine expression. a The messenger RNA (mRNA) expression levels of interferon-γ (IFN-γ), but not interleukin (IL)-17A or tumor necrosis factor-α (TNF-α), were increased in K562 cells 24 h after transfection of miR-29b-1-5p mimic compared with those transfected with scrambled oligonucleotides. b The mRNA expression levels of IFN-γ, but not IL-17A or TNF-α, were increased in K562 cells after coculture with IL-23 (20 ng/ml) compared with those cultured with medium alone. c The K562 cells transfected with miR-29b-1-5p mimic or scrambled oligonucleotides were cultured with IL-23 (20 ng/ml) for 24 h, and there was no difference in the mRNA expression levels of IFN-γ, IL-17A, or TNF-α between these two groups