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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: How much allopurinol does it take to get to target urate? Comparison of actual dose with creatinine clearance-based dose

Fig. 2

Effect of increasing the amount of allopurinol (milligrams) above the recommended creatinine-clearance-based dose (R+) on serum urate (SU) (a), percentage change in SU (b), delta SU (c) and plasma oxypurinol (d) at month 12 of the dose escalation phase. Difference in SU (e), percentage change in SU (f), delta SU (g) and plasma oxypurinol (h) at month 12 of the dose escalation phase in those who did or did not achieve target SU at month 12 of the dose escalation phase. *p < 0.05

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