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Table 1 Characteristics of the RA patients at presentation with clinically suspect arthralgia and at first identification of clinical arthritis and age-matched symptom-free volunteers

From: Sequence of joint tissue inflammation during rheumatoid arthritis development

  At presentation with arthralgia (n = 31) At presentation with RA (n = 31) Age-matched symptom-free volunteers (n = 62)
Age (years), mean (SD) 44 (14) 44 (13)
Female sex, n (%) 22 (71) 38 (61)
Symptom duration (weeks), median (IQR) 17 (9–32) n/a
Presence of morning stiffness ≥ 60 min, n (%) 11 (35) 24 (77) 0 (0)
68-TJC, median (IQR) 5 (4–10) 7 (5–12) 0 (0–0)
66-SJC, median (IQR) 0 (0–0) 2 (1–5) 0 (0–0)
Increased CRP (≥ 5 mg/L), n (%) 6 (19) 7 (29) n/a
Autoantibody status
 IgM-RF-positive (≥ 3.5 IU/mL), n (%) 13 (42) 13 (42) n/a
 ACPA-positive (≥ 7 U/mL), n (%) 9 (29) 9 (29) n/a
 Any antibody-positive (either RF or ACPA) 16 (52) 16 (52) n/a
  1. ACPA anti-citrullinated peptide antibody, CRP C-reactive protein, IgM-RF immunoglobulin M rheumatoid factor, IQR interquartile range, n/a not applicable or not assessed, RA rheumatoid arthritis, RF rheumatoid factor, SD standard deviation, SJC swollen joint count, TJC tender joint count