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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: The effect of the cholinergic anti-inflammatory pathway on collagen-induced arthritis involves the modulation of dendritic cell differentiation

Fig. 3

GTS-21 downregulated the expression of CD80 and major histocompatibility complex II (MHC II) on the surface of dendritic cells (DCs) in the spleen. a, c Histograms of MHC II and CD80 in CD11c+ cells are shown. b, d The changes of mean fluorescence intensity (MFI) of MHC II and CD80 were analyzed. Data are expressed as the mean ± standard deviation (n = 8). *P <0.05 versus the control group; #P <0.05 versus the model group; &P <0.05 versus the vagotomy group

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