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Table 1 Study participant characteristics

From: Carotid artery volumetric measures associate with clinical ten-year cardiovascular (CV) risk scores and individual traditional CV risk factors in rheumatoid arthritis; a carotid-MRI feasibility study

Variable Expressed as Patients with RA Controls
n = 64 n = 24
Demographics
 Age, years mean, SD 59.6 (9.4) (range 31, 78) 51.8 (11.7) (range 35–80)
 Female n (%) 45 (70.3) 13 (54.2)
 Ethnicity n (%) 60 (94.0) white 21/22 (95.8) white
CV risk profile
 PMH hypertension n (%) 22 (34.4) 1/21 (4.2)
 PMH hypercholesterolaemia n (%) 16 (25.0) 1/21 (4.2)
 Smoking status:
  Never n (%) 28 (43.8) 11/21 (52.4)
  Ex-smoker 28 (43.8) 8/21 (38.1)
  Current 8 (12.5) 2/21 (9.5)
 Alcohol intake, units/week median (IQR) 2 (0, 8) (n = 63) 1 (0, 6) (n = 21)
 FHx premature CVDa n (%) 14 (21.9) 4/20 (16.7)
 Five or more fruit/vegetables daily intake, days/week median (IQR) 5 (4, 7) (n = 63) 6 (4, 7) (n = 19)
 Moderate exercise, mins/week median (IQR) 40 (0, 156) (n = 62) 60 (0, 240) (n = 20)
 Number of current anti-hypertensives n (%) 8 (12.5) on 1 drug 1/21 (4.8) on 2 drugs
8 (12.5) on 2 drugs
1 (1.6) on 3 drugs
 Current use of statin n (%) 11 (17.2) 1/21 (4.2)
 BMI mean, SD 25.8 (3.3) 25.2 (3.4)
 Waist/hip ratio mean, SD 0.84 (0.08) (n = 62) 0.82 (0.10) (n = 21)
 Systolic BP, mmHg mean, SD 134 (20) 125 (14) (n = 23)
 Diastolic BP, mmHg mean, SD 80 (12) 74 (10) (n = 23)
Fasting blood tests
 Fasting glucose, mmol/L mean, SD 4.9 (1.0) (n = 60) 4.7 (0.5) (n = 19)
 Fasting total cholesterol, mmol/L mean, SD 5.3 (1.1) (n = 63) 5.1 (1.0) (n = 19)
 Fasting HDL-C, mmol/L mean, SD 1.6 (0.4) (n = 61) 1.6 (0.4) (n = 19)
 Fasting LDL-C, mmol/L mean, SD 3.1 (1.0) (n = 61) 3.0 (0.9) (n = 19)
 Fasting TC/HDL-C ratio mean, SD 3.4 (1.1) (n = 61) 3.3 (1.0) (n = 19)
 Fasting triglycerides, mmol/Lb geometric mean 1.1 (n = 63) 1.0 (n = 19)
 HOMA-IRb geometric mean 1.06 (n = 60)c 1.13 (n = 20)
 NT-proBNP, pg/mlb geometric mean 53.3 (n = 60) 40.2 (n = 20)
Ten-year clinical risk scores
 Framingham: median (IQR) 14.5 (6.3, 27.9)d 4.4 (1.3, 14.4) (n = 18)
14.6 (8.1, 29.1)e
 Joint British Societies 2: median (IQR) 11.9 (4.9, 20.2)d 3.9 (0.8, 11.5) (n = 18)
12.0 (6.1, 22.2)e
  1. BMI body mass index, BP blood pressure, CVD cardiovascular disease, FHx family history, HOMA-IR homeostasis model of assessment of insulin resistance, LDL-C low-density lipoprotein cholesterol, NT-proBNP N-terminal pro-brain natriuretic peptide, PMH past medical history of, RA rheumatoid arthritis, TC/HDL-C total cholesterol/high-density lipoprotein cholesterol ratio
  2. aDefined as first-degree relative with a history of CVD when 60 years old or younger if female, and 55 years old or younger if relative
  3. bVariables log transformed prior to analysis
  4. cExcluding outlier: 1.01 (n = 59)
  5. dAdjusted to 2010 European League Against Rheumatism (EULAR) guidelines [15]
  6. eAdjusted to 2017 EULAR guidelines [34]