Skip to main content

Advertisement

Table 3 Carotid artery magnetic resonance imaging measures in study participants

From: Carotid artery volumetric measures associate with clinical ten-year cardiovascular (CV) risk scores and individual traditional CV risk factors in rheumatoid arthritis; a carotid-MRI feasibility study

Carotid artery variable Patients with RA, n = 64 Controls, n = 24 Unadjusted differences in RA group from controls Mean difference adjusted for age and sex Mean difference adjusted for age, sex and CV risk factorsb
Mean (95% CI) P value B (95% CI) P value B (95%) P value
Mean wall thickness, mm 1.051 (0.125) 1.029 (0.129) 0.022 (− 0.038, 0.082) 0.460 0.002 (− 0.060, 0.064) 0.940 −0.009 (− 0.079, 0.060) 0.790
Minimum wall thickness, mm 0.747 (0.096) 0.718 (0.107) 0.029 (− 0.019, 0.076) 0.230 0.013 (− 0.036, 0.063) 0.591 0.000 (− 0.056, 0.056) 0.990
Maximum wall thickness, mm 1.498 (0.330) 1.530 (0.311) − 0.031 (− 0.186, 0.123) 0.688 − 0.050 (− 0.217, 0.118) 0.556 − 0.045 (− 0.237, 0.148)c 0.646
Wall volumea, ul 234.528 (45.187) (n = 60) 225.613 (46.751) 8.914 (−13.010, 30.839) 0.421 −5.053 (−26.236, 16.131) 0.636 −5.479 (−28.979, 18.021) 0.644
Luminal volumea, ul 383.408 (116.277) (n = 60) 368.753 (105.625) 14.655 (−39.82, 69.135) 0.594 −0.430 (−55.585, 54.726) 0.988 −8.792 (−71.799, 54.215) 0.782
Wall volume indexeda 0.385(0.046) (n = 60) 0.385 (0.040) 0.001 (− 0.020, 0.022) 0.930 0.001 (−0.023, 0.024) 0.963 0.001 (−0.026, 0.027) 0.952
Wall volume indexed/BSA 0.216 (0.036) (n = 60) 0.221 (0.032) −0.005 (− 0.021, 0.012) 0.567 − 0.11 (− 0.029, 0.006) 0.201 −0.008 (− 0.028, 0.012) 0.430
  1. CV cardiovascular, BSA body surface area, RA rheumatoid arthritis
  2. aOf 6 mm length of carotid artery. Carotid wall volume indexed calculated by carotid wall volume/(carotid wall volume + luminal volume)
  3. bCV risk factors defined as: hypertension (history of hypertension or anti-hypertensive agent), dyslipidaemia (history of dyslipidaemia, on lipid-lowering medication or total cholesterol/high-density lipoprotein cholesterol ratio > 6), ever smoked and family history of premature cardiovascular disease
  4. cHeteroskedasticity of residuals therefore robust standard errors employed to compensate