Fig. 4
The changes in autophagosome levels evidenced by Cyto-ID mean fluorescence intensity in circulating (a) lymphocytes, b monocytes, and (c) granulocytes and the change in (d) serum tumor necrosis factor-α levels as well as (e) interleukin (IL)-6 levels after 6-month therapy in patients with rheumatoid arthritis. Data are presented as the mean ± SEM. *p < 0.05, **p < 0.005, ***p < 0.001 vs. before treatment, as determined by Wilcoxon signed-rank test