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Table 1 Demographic and clinical data of the ICON study population

From: Vitamin D deficiency is associated with higher disease activity and the risk for uveitis in juvenile idiopathic arthritis - data from a German inception cohort

  ICON patients with 25(OH)D measurement All patients of the ICON study
Number 360 954
Female (%) 67.5 67.2
Age at study inclusion, years, mean (SD) 7.1 (4.6) 7.9 (4.8)
Duration between symptom onset and diagnosis, months, median (IQR) 3 (2–7) 3 (1–6)
Duration between diagnosis and ICON enrollment, months, median (IQR) 1.4 (0.5–4.4) 1.5 (0.4–4.7)
Patients
 - on DMARD at inclusion, n (%) 178 (49) 471 (49)
 - on MTX at inclusion, n (%) 164 (46) 441 (46)
 - on biologic drug at inclusion, n (%) 14 (4) 49 (5)
Median (IQR) duration (months) of
 - DMARD use at inclusion 1.2 (0.5–3.4) 1.2 (0.5–3.5)
 - MTX use at inclusion 1.2 (0.5–3.5) 1.2 (0.5–3.4)
 - Biologic drug use at inclusion 1.1 (0.4–2.9) 0.9 (0.3–2.9)
ANA positive at study inclusion, n (%) 228 (63) 517 (54)
  ILAR category, n (%) ILAR category, n (%)
Systemic arthritis 15 (4) 35 (4)
Oligoarthritis 173 (48) 445 (47)
Psoriatic arthritis 18 (5) 39 (4)
Enthesitis-related arthritis 30 (8) 100 (11)
Polyarthritis, rheumatoid factor positive 5 (1) 15 (2)
Polyarthritis, rheumatoid factor negative 96 (27) 252 (26)
Other arthritis 23 (6) 68 (7)
  1. ICON Inception cohort of newly diagnosed patients with juvenile idiopathic arthritis, 25(OH)D: 25(OH) vitamin D, SD standard deviation, IQR interquartile range, DMARD disease-modifying antirheumatic drug, MTX methotrexate, ANA antinuclear antibody, ILAR International League of Associations for Rheumatology