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Table 1 Demographic and clinical data of the ICON study population

From: Vitamin D deficiency is associated with higher disease activity and the risk for uveitis in juvenile idiopathic arthritis - data from a German inception cohort

 

ICON patients with 25(OH)D measurement

All patients of the ICON study

Number

360

954

Female (%)

67.5

67.2

Age at study inclusion, years, mean (SD)

7.1 (4.6)

7.9 (4.8)

Duration between symptom onset and diagnosis, months, median (IQR)

3 (2–7)

3 (1–6)

Duration between diagnosis and ICON enrollment, months, median (IQR)

1.4 (0.5–4.4)

1.5 (0.4–4.7)

Patients

 - on DMARD at inclusion, n (%)

178 (49)

471 (49)

 - on MTX at inclusion, n (%)

164 (46)

441 (46)

 - on biologic drug at inclusion, n (%)

14 (4)

49 (5)

Median (IQR) duration (months) of

 - DMARD use at inclusion

1.2 (0.5–3.4)

1.2 (0.5–3.5)

 - MTX use at inclusion

1.2 (0.5–3.5)

1.2 (0.5–3.4)

 - Biologic drug use at inclusion

1.1 (0.4–2.9)

0.9 (0.3–2.9)

ANA positive at study inclusion, n (%)

228 (63)

517 (54)

 

ILAR category, n (%)

ILAR category, n (%)

Systemic arthritis

15 (4)

35 (4)

Oligoarthritis

173 (48)

445 (47)

Psoriatic arthritis

18 (5)

39 (4)

Enthesitis-related arthritis

30 (8)

100 (11)

Polyarthritis, rheumatoid factor positive

5 (1)

15 (2)

Polyarthritis, rheumatoid factor negative

96 (27)

252 (26)

Other arthritis

23 (6)

68 (7)

  1. ICON Inception cohort of newly diagnosed patients with juvenile idiopathic arthritis, 25(OH)D: 25(OH) vitamin D, SD standard deviation, IQR interquartile range, DMARD disease-modifying antirheumatic drug, MTX methotrexate, ANA antinuclear antibody, ILAR International League of Associations for Rheumatology