Skip to main content

Table 3 Risk of developing uveitis in relation to 25(OH)D level (mean of both measurements) and other parameters

From: Vitamin D deficiency is associated with higher disease activity and the risk for uveitis in juvenile idiopathic arthritis - data from a German inception cohort

  Patients with uveitis
n = 61
Patients without uveitis
n = 299
Hazard ratio 95% CI p value
25(OH)D level, mean (SD), ng/ml 21.0 (6.8) 22.4 (8.0) 0.95 0.91; 0.99 0.022
Female sex, n (%) 45 (74) 198 (66) 1.32 2.56; 0.68 0.414
Age at JIA onset, mean (SD), years 4.0 (2.9) 7.8 (4.6) 0.84 0.77; 0.93 0.001
Oligoarticular JIA onset, n (%) 41 (67) 132 (44) 1.20 0.60; 2.41 0.601
ANA positivity at study inclusion, n (%) 58 (95) 170 (57) 5.07 1.50; 17.15 0.009
cJADAS-10a (range 0–30), mean (SD) 5.9 (3.9) 4.8 (3.2) 1.22 1.14; 1.31 <  0.001
MTX treatmentb, n (%) 31 (51) 235 (79) 0.29 0.15; 0.57 < 0.001
  1. 25(OH)D 25(OH) vitamin D, JIA juvenile idiopathic arthritis, ANA antinuclear antibodies, MTX methotrexate, cJADAS Clinical Juvenile Arthritis Disease Activity Score
  2. acJADAS-10: mean score in patients with uveitis were calculated until occurrence of uveitis, in patients without uveitis mean cJADAS-10 score was calculated until 3-year follow up
  3. bMTX: patients with uveitis, ever treated with MTX until occurrence of uveitis; patients without uveitis, ever treated until 3-year follow up