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Table 2 Association between ultrasound abnormalities and development of clinical arthritis/rheumatoid arthritis analyzed at the patient level

From: The value of joint ultrasonography in predicting arthritis in seropositive patients with arthralgia: a prospective cohort study

Ultrasound abnormalities Arthritis, yes Arthritis, no OR (95% CI) p value PPV NPV
Outcome: clinical arthritis n = 51 n = 112     
 Synovial thickeninga (16 joints) 19 (37%) 30 (27%) 1.6 (0.8–3.3) 0.18c 39% 72%
 Synovial thickening (10 joints, no MTP) 10 (20%) 4 (4%) 6.6 (1.9–22.2) < 0.01d 71% 72%
 Power Dopplera (16 joints)b 2 (4%) 5 (5%) 0.9 (0.1–4.7) 1.0.d 29% 69%
Outcome: 2010 RA criteria n = 44 n = 119     
 Synovial thickening (16 joints) 17 (39%) 32 (27%) 1.7 (0.8–3.6) 0.15c 35% 76%
 Synovial thickening (10 joints, no MTP) 10 (23%) 4 (3%) 8.5 (2.4–28.7) < 0.01d 71% 77%
 Power Doppler (16 joints)b 2 (5%) 5 (4%) 1.1 (0.2–5.9) 1.0d 29% 73%
  1. CI confidence interval, MTP metatarsophalangeal, NPV negative predictive value, OR odds ratio, PPV positive predictive value, RA rheumatoid arthritis
  2. aResults are presented for synovial thickening and power Doppler in at least one joint
  3. bSame results when excluding MTP joints
  4. cChi-square test
  5. dFisher’s exact test