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Table 3 Added value of ultrasound over clinical parameters according to a clinical prediction rule

From: The value of joint ultrasonography in predicting arthritis in seropositive patients with arthralgia: a prospective cohort study

Ultrasound abnormalities Arthritis, yes Arthritis, no OR (95% CI)d p value
Clinical prediction rule risk-groupsa n = 51 n = 112
Synovial thickeningb (16 joints)    1.5 (0.7–3.4) 0.3
Clinical prediction rule    3.5 (2.2–5.4) < 0.01
 Low risk 2/8 (25%) 19/67 (28%)   
 Intermediate risk 5/13 (38%) 5/25 (20%)   
 High risk 12/30 (40%) 6/20 (30%)   
Synovial thickening (10 joints, no MTP)    6.1 (CI 1.6–23.2) < 0.01
Clinical prediction rule    3.5 (CI 2.2–5.5) < 0.01
 Low risk 0/8 (0%) 3/67 (4%)   
 Intermediate risk 4/13 (31%) 1/25 (4%)   
 High risk 6/30 (20%) 0/20 (0%)   
Power Dopplerb (16 joints)c    1.7 (0.3–10.2) 0.5
Clinical prediction rule    3.6 (2.3–5.6) < 0.01
 Low risk 0/8 (0%) 4/67 (6%)   
 Intermediate risk 2/13 (15%) 1/25 (4%)   
 High risk 0/30 (0%) 0/20 (0%)   
  1. ACPA anti-citrullinated protein antibody, CI confidence interval, MTP metatarsophalangeal, OR odds ratio, RF rheumatoid factor
  2. aRisk groups based on the clinical prediction rule described in reference number 4
  3. bResults are presented for synovial thickening and power Doppler in at least one joint (present, %)
  4. cSame results when excluding MTP joints
  5. dLogistic regression analysis (note that the prediction rule risk groups were combined)