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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis

Fig. 2

Renal bradykinin 1 receptor (B1R) and B2R expression in MRL/lpr mice and B6 mice as assessed by immunohistochemistry (IHC). IHC was used to monitor renal B1R and B2R expression in control and lupus mice. Kidney sections obtained from 4-month-old C57BL/6 J and MRL/lpr mice were stained with the following primary antibodies: rabbit anti-mouse B1R antibody (Bioss Inc. Woburn, MA, USA) and rabbit anti-mouse B2R antibody (Bioss Inc. Woburn, MA, USA). IHC analysis indicated elevated renal B1R expression in MRL/lpr mice (b) compared with B6 mice (a). B6 mice demonstrated stronger renal B2R expression than MRL/lpr mice (c, d). Shown data are representative of IHC staining from five B6 mice and five MRL/lpr mice

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Arthritis Research & Therapy

ISSN: 1478-6362

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